| 摘要 |
A compound 1-(3-azido-2,3-dideoxy- beta -D-erythro-pentofuranoxyl)-5-methyl-2(1H)-pyrimidinone and its use in a method of generating (forming, providing) 3'-azido-3'-deoxythymidine (zidovudine sometimes referred to as AZT) in the body of an animal (a mammal such as human) by systemically administering 1-(3-azido-2,3-dideoxy- beta -D-erythro-pentofuranosyl)-5-methyl-2(1H)-pyriminone to said animal (mammal such as a human) is disclosed. AZT is approved and used for treating HIV infections, e.g., AIDS and ARC in humans and also has activity against gram-negative bacteria in animals.
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