| 摘要 |
PURPOSE:To easily obtain the title compound as e.g. an intermediate for medicines or pesticides without after-treatment problems by reaction between a dihalogenated hydrocarbon and an alkali metal salt of aliphatic carboxylic acid in the presence of each specific phase-transfer catalyst and solvent. CONSTITUTION:In the presence of a phase-transfer catalyst of formula I (R is hydrocarbon residue; X is halogen), a reaction is made, at 20-300 deg.C, (esp. 30-100) deg.C in an acetic alkyl ester solvent, between (A) a dihalogenated hydrocarbon of formula II (X1 and X2 are each halogen differing from each other; A is alkylene) and (B) and alkali metal salt of aliphatic carboxylic acid of formula III (R is alkyl; M is alkali metal) using pref. 1.0-1.5mols per mol of the compounds A of the compound B, thus obtaining the objective compound of formula IV (X3 is halogen). The phase-transfer catalyst is e.g. tetramethylammonium chloride; and the solvent is e.g. n-butyl acetate. |
