发明名称 ENDOGENOUS BRAIN FACTOR, METHOD FOR OBTAINING IT AND THERAPEUTIC AND DIAGNOSTIC USES THEREOF
摘要 <p>An endogenous brain factor or a fragment thereof, acting on the serotoninergic functions and having an essentially peptide nature, a molecular weight of approximately 3500 daltons, and a pK of about 5. It is heat stable and soluble in acetone up to 75 %, in primary alcohols up to 90 %, in water and in an acidic medium up to 1M, is 70 % inactive in acetonitrile, reacts negatively with anisaldehyde, and can be obtained by extraction from the cerebral cortex and by chromatographic purification.</p>
申请公布号 WO1991011463(A1) 申请公布日期 1991.08.08
申请号 FR1991000085 申请日期 1991.02.05
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