发明名称 ALPHA'-ALKYL-4-AMINO-3-QUINOLINEMETHANOLS, 1-(4-ARALKYLAMINO-3-QUINOLINYL) ALAKNONES, THEIR USE AS MEDICAMENTS
摘要 There are described compounds of the formula <CHEM> where X is hydrogen, halogen, loweralkyl, loweralkoxy or trifluoromethyl; R is - @-R4 or -@@-R4, R4 being loweralkyl; R1 is hydrogen, loweralkyl or arylloweralkyl; R2 is hydrogen, loweralkyl or arylloweralkyl; and R3 is loweralkyl, with the proviso that when R is acetyl, R3 is methyl and X is hydrogen, R1 and R2 are not both hydrogen, or pharmaceutically acceptable acid addition salts thereof, which are useful for enhancing memory and for treating Alzheimer's disease.
申请公布号 PH25571(A) 申请公布日期 1991.08.08
申请号 PH19240000357 申请日期 1987.08.24
申请人 HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED 发明人 RICHARD CHARLES EFFLAND;JOSEPH THOMAS KLEIN
分类号 A61K31/47;A61P25/28;A61P43/00;C07D215/42;C07D215/44 主分类号 A61K31/47
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