EXTRACELLULAR FORM OF THE HUMAN FIBROBLAST GROWTH FACTOR RECEPTOR

摘要

A polypeptide is disclosed which is capable of binding specifically human fibroblast growth factor (bFGF) and human acidic fibroblast growth factor (aFGF) and which has: (a) the sequence shown or a part of the said sequence or (b) a said sequence (a) modified by one or more amino acid substitutions, insertions and/or deletions and/or by an extension at either or each end. A process for preparing the polypeptide, pharmaceutical compositions containing it and a DNA sequence which encodes it are also disclosed.