发明名称 IMPROVED CYCLODEXTRIN BASED ERYTHROPOIETIN FORMULATION
摘要 <p>The present invention relates to a new pharmaceutical composition for parenteral and local administration comprising an aqueous solution of erythropoietin and a β-/ or η-cyclodextrin hydroxyalkyl derivative. The invention also relates to novel lyophilized or spray-dried erythropoietin compositions comprising a β- or η-cyclodextrin hydroxyalkyl derivative, to processes for preparing such aqueous, lyophilized or spray-dried compositions and to a method for simultaneously stabilizing erythropoietin in an aqueous solution and preventing it from being adsorbed to surfaces.</p>
申请公布号 WO1991011200(A1) 申请公布日期 1991.08.08
申请号 EP1991000173 申请日期 1991.01.25
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