| 摘要 |
<p>A recombinant adenovirus acting as a vector for an antigen-producing gene (e.g. a rabies glycoprotein gene) comprises a CAV-2 strain modified to contain the promoter-gene sequence within the region from the SmaI site close to the end of the inverted terminal repeat up to the promoter for the early region 4 (E4). To assist replication the recombinant virus is transfected into a cell line expressing Ela proteins. The recombinant virus is used for the production of a corresponding vaccine.</p> |
