NEUTRALIZING AND/OR ADCC MEDIATING MONOCLONAL HIV ANTIBODY

摘要

Monoclonal antibodies (MAbs) to human immunodeficiency virus (HIV) mediating neutralization of HIV and/or antibody-dependant cellular cytotoxity to HIV, a method to prepare these MAbs and hybridomas producing these MAbs are disclosed. The MAbs have utility i.a. in preventing spread of HIV infections, as a passive or active vaccine, for assay of HIV antigens, and to identify a neutralizing epitope in preparations for immunization.