发明名称 Novel fungal expression system.
摘要 The invention relates to the field of genetic engineering and provides novel DNA molecules comprising a fungal promoter. The novel DNA molecules are useful for the construction of hybrid vectors expressing genes in filamentous fungi. Objects of the invention are novel DNA molecules comprising the A. niger pki promoter, hybrid vectors useful for the expression of structural genes under the control of said promoter, hosts transformed with the novel hybrid vectors, and processes for the production of the novel DNA molecules, hybrid vectors, and transformed hosts and for the production of recombinant polypeptides by means of said transformed hosts.
申请公布号 EP0439997(A1) 申请公布日期 1991.08.07
申请号 EP19900811008 申请日期 1990.12.20
申请人 CIBA-GEIGY AG 发明人 DE GRAAFF, LEENDERT HENDRIK;VAN DEN BROECK, HENRIETTE CATHARINA;VISSER, JACOB, PROF.;BUXTON, FRANK, DR.
分类号 C12N1/15;C07K14/56;C12N1/21;C12N9/12;C12N9/24;C12N9/88;C12N15/09;C12N15/20;C12N15/54;C12N15/80;C12R1/19;C12R1/685 主分类号 C12N1/15
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