摘要 |
1,3-Dithiol-2-ylidene derivs. of formula (I) are prepd. by reacting a cpd. of formula (II) with a cpd. of formula HNR2R3. In the formulas, R1= C1-5 alkyl; R2= H or C1-4 alkyl; R3= phenyl substd. by one or more radical selected from C1-3 alkyl, alcoxy, acyloxy, acylamide, hydroxy, carboxy, amino, nitor, halogen, trifluoromethyl of C1-3 alkoxycarbonyl, C3-6 cycloalkyl, tetrahydrothiopen-2-on- 3-yl, 2-thiazolyl, 2-benzothiazolyl, 5- methyl-3-isoxazolyl or 5-tetrazolyl; R4= sec.-or tert. -butyl, lower alkoxy or benzyloxy. (I) may be used in the treatment of liver disorders.
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