| 摘要 |
Substd. aminomethyl-isothiourea derivs. of formula (I) are presented: R1-R6 each= alk(en)yl or alkynyl (all opt. subtsd. by halogen), alkoxyalkyl, cycloalk(en)ly, opt. substd. aralkyl, naphthyl, pyridyl, phenyl (substd. by X1,X2 or X3) or a gp. of formula (II); X1-X3 each= H, (cyclo)alkyl, alkoxy, MeCO, halocalkyl, halogen, CF3, NO2, OH, benzyl, Ph, PhO, or PhS; Y1 and Y2 each=H, lower alkyl ro alkoxy, halogen, CF3; W=CR7R8, O, CO or OCH2; m= 0-2; R7 and R8 each= H or lower alkyl; R2-6 may be H; and R4 and R5, or R6 forms with (CH2)n (n= 2-4), CH2OCH2 or CH2SCH2 (at least one of R4-R6 is H). (I) are useful as intermediates in a synth. of 1,3,5-thiadiazin-4- one derivs.
|
