| 摘要 |
A novel process for the preparation of partially fluorinated alcohols of the formula (I), …<IMAGE>… in which… R and R<1> are identical or different and represent alkyl which is mono- or polysubstituted by fluorine, cycloalkyl which is mono- or polysubstituted by fluorine or R and R<1> together represent the group -(CF2)n-, in which n represents 2, 3 or 4,… characterised in that … … a) compounds of the formula (II), …<IMAGE>… are reacted with an alcohol of the formula (III), …<IMAGE>… in the presence of a base to give compounds of the formula (IV), …<IMAGE>… and … b) the compounds of the formula (IV), if appropriate after their isolation, are hydrogenated catalytically using hydrogen, either … alpha ) in the absence of a base to give compounds of the formula (I), or … beta ) hydrogenated in the presence of a base to give compounds of the formula (V), …<IMAGE>… and the compounds of the formula (V), if appropriate after their isolation, are converted into compounds of the formula (I), using ether-cleaving agents, and 2,2,3,3,4,4-hexafluorocyclopentanol as novel partially fluorinated alcohol. … |
