| 摘要 |
COMPOSITION, DEVICE AND METHOD OF ASSAYING FOR A PEROXIDATIVELY ACTIVE SUBSTANCE A new and improved test device and method of determining the presence or concentration of a peroxidatively active substance, such as hemoglobin, in a test sample are disclosed. The test device includes a test pad comprising a suitable carrier matrix incorporating an indicator reagent composition capable of interacting with a peroxidatively active substance to produce a detectable or measurable response. In addition, a new and improved indicator reagent composition, comprising an indicator dye, such as a redox indicator, like a benzidine indicator; a hydroperoxide; an amine borate compound having the general structural formula: or wherein R1, R2, and R3 are, independently, methyl groups or ethyl groups, and m, n and p are numerals ranging from one to about three; and a buffer, is incorporated into a suitable carrier matrix to provide a more accurate and trustworthy assay of a test sample for a peroxidatively active substance. The improved method and composition are especially useful in the assay of urine for occult blood. MS-1603 |
