发明名称 1-AZETIDYL AND 1-HEXAMETHYLENIMINE ALKYL OR ARYL BISPHOSPHONIC ACIDS AND THEIR USE AS PHARMACOLOGICAL AGENTS
摘要 <p>This invention relates to compounds having: (A) a bisphosphonic acid endgroup; (B) an azetidine- or hexamethylenimine-derived azacyclic endgroup; and (C) an alkyl and/or aryl group linking the bisphosphonic acid and azacyclic groups through the nitrogen atom of the azacyclic group. These compounds are useful as agents for regulating the metabolism of polyvalent ions, particularly calcium. This invention relates also to pharmaceutical compositions including said compounds and to methods of treating conditions for which said metabolism is involved by using said compounds.</p>
申请公布号 WO1991010646(A1) 申请公布日期 1991.07.25
申请号 US1991000055 申请日期 1991.01.03
申请人 发明人
分类号 主分类号
代理机构 代理人
主权项
地址