摘要 |
NEW MATERIAL:A peptide expressed by the formula. USE:Used as analgesic agent or enkephalin-decomposing enzyme inhibitor useful as adjuvant for reinforcing analgesic action with morphine, etc. PREPARATION:At first, medulla spinalis of bovine is minced and homogenized by adding 1M acetic acid, then extracted. Next, resultant extract is subjected to column chromatography, gel filtration or high-performance liquid chromatography, etc., and isolated, then purified to afford the aimed heptapeptide. |