| 发明名称 |
Potentiation of erythropoiesis |
| 摘要 |
A method for modulating the rate of erythropoiesis in human hematopoietic progenitor cells. FRP is found to be an efficacious potentiator of, and inhibin a suppressor of, erythropoietin-induced differentiation. FRP and inhibin are shown to be functional antagonists of each other, and thus represent an effective means for modulating erythropoiesis in a number of disease states which are directly caused by or associated with an abnormal rate of erythropoiesis.
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| 申请公布号 |
US5032507(A) |
申请公布日期 |
1991.07.16 |
| 申请号 |
US19870120470 |
申请日期 |
1987.11.13 |
| 申请人 |
THE SALK INSTITUTE FOR BIOLOGICAL STUDIES;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;SCRIPPS CLINIC AND RESEARCH FOUNDATION |
发明人 |
YU, JOHN;YU, ALICE L.;VAUGHAN, JOAN;RIVIER, JEAN E. F.;VALE, JR., WYLIE W. |
| 分类号 |
A61K38/00;A61K38/04;A61K38/22;A61P7/00;C07K14/435;C07K14/575 |
主分类号 |
A61K38/00 |
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