发明名称 |
Gene transfer using transformed, neodetermined, embryonic cells |
摘要 |
This invention is directed to a method for the preparation of carrier cells capable of delivering exogenous genetic material to a particular tissue of the body by means of embryonic cells competent to develop into that tissue, and essentially only that tissue, said cells bearing the exogenous genetic material. The preferred carrier cells are mesodermal cells of the yolk sac or embryonic forebrain or midbrain cells, and the desired genetic material is preferably introduced into the cells by in vitro transformation with an amphotrophic retroviral vector.
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申请公布号 |
US5032407(A) |
申请公布日期 |
1991.07.16 |
申请号 |
US19870004077 |
申请日期 |
1987.01.16 |
申请人 |
OHIO UNIVERSITY EDISON ANIMAL BIOTECHNOLOGY CENTER |
发明人 |
WAGNER, THOMAS E.;REED, MICHAEL A.;CORN, BARBARA J. |
分类号 |
A61K48/00;C12N5/073 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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