UREIDO DERIVATIVES OF POLY-4-AMINO-2-CARBOXY-1-METHYL COMPOUNDS

摘要

The invention relates to ureido derivatives of substituted pyrroles of formu la (I) wherein each of m and n, being the same, is an integer of 1 to 3; W is oxygen of sulphur; each of the B groups, which are the same, is a) a saturated or unsaturated, carbo- cyclic or condensed carbocylic ring substituted by one or more acid groups; b) a saturated or unsaturated, heteromonocyclic or heterobicyclic ring, containing one or more heteroatoms chosen from nitrogen , oxygen and sulphur, substituted by one or more acid groups; c) a pyranyl or furanyl sugar residue substituted by one or mor e acid groups; or d) a -CH2(CHA) r CH2A group, wherein each A group, being the same or different, is an acid group and r is 0, 1 or 2; and the pharmaceutically acceptable salts thereof, which are useful as angiogenesis inhibitors.