发明名称 |
NEW METHOD OF PROTECTION OF THE CARBOXY GROUPS IN THE CHEMISTRY OF BETA-LACTAM COMPOUNDS |
摘要 |
<p>The present invention relates to a new method of protection of the carboxy group in the chemistry of the compounds of beta -lactam type. According to such a method, the carboxy group is protected by being transformed into its corresponding phenyl-acetoxy-methyl ester, which is then removed by an enzymatic route by means of penicillinacylase. In particular, if the beta -lactam compound also bears a phenyl-acetamidic substituent, this latter is simultaneously hydrolysed during the same step of removal of the carboxy function protecting group.</p> |
申请公布号 |
EP0336511(A3) |
申请公布日期 |
1991.07.03 |
申请号 |
EP19890200832 |
申请日期 |
1989.03.31 |
申请人 |
SCLAVO S.P.A. |
发明人 |
FUGANTI, CLAUDIO;BALDARO, EVA;FAIARDI, DANIELA;LAZZARINI, AMERIGA |
分类号 |
C07D499/00;C07D499/08;C07D501/04;C07D501/10;C12P35/00;C12P35/02;C12P37/00;(IPC1-7):C07D501/04 |
主分类号 |
C07D499/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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