发明名称 ARYLSULFATASE
摘要 The present invention relates to an arylsulfatase of microbial origin. The enzyme may be linked to an antibody against a tumor-associated antigen and the resulting conjugate used in conjuction with a sulfated prodrug of a 4 min -demethylepipodophyllotoxin glucoside derivative, particularly etoposide in cancer chemotherapy.
申请公布号 JPH03155781(A) 申请公布日期 1991.07.03
申请号 JP19900279490 申请日期 1990.10.19
申请人 BRISTOL MYERS SQUIBB CO 发明人 SAWADA YOSUKE;UEKI TOMOKAZU;YAMAMOTO SOJI;TOMITA KOJI;FUKAGAWA YASUO;OKI SHUNICHI
分类号 A61K47/48;C12N1/20;C12N9/16;C12R1/465;C12R1/765 主分类号 A61K47/48
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