Thienobenzoxepin- and naphthothiophene-derivatives, a process and intermediates for their preparation and their use as medicaments.

摘要

The present invention relates to thieno[3,2-c]benzoxepins of formula 1 and naphtho[2,3-b]thiophenes of formula 2, intermediates thereof and a process for their preparation. The compounds of the invention have analgetic properties and can, therefore, be used as medicaments. <CHEM> <CHEM> wherein R is loweralkyl or arylloweralkyl, X and Y are independently hydrogen, loweralkyl, halogen, loweralkoxy, or trifluoromethyl; W is CH2, CHOH, or C=O; and n is 1 or 2; an optical isomer or pharmaceutically acceptable salt thereof.