发明名称 DERIVATIVES OF GUANINE
摘要 Antivirally active compounds of the formula I wherein A is (Aa) or (Ab) wherein m is 1 or 2, n is 1 or 2, whereby m is 1 when n is 2 and m is 2 when n is 1, R? is (CH2)pOH, NHCONH2 or COR?, R? is hydrogen, hydroxy or amino, p is 1 to 4, R? and R? are independently selected from hydrogen or (CH2)pOH, with the proviso that at least one of R? or R? is hydrogen; or R? and R? together constitute an additional carbon-carbon bond to form an alkyne; or a physiologically acceptable salt, geometric or optical isomer thereof; processes for preparation of said compounds, pharmaceutical preparations containing the compounds, methods for treatment of virus infections and the medical use of the compounds.
申请公布号 CA1285560(C) 申请公布日期 1991.07.02
申请号 CA19840470490 申请日期 1984.12.19
申请人 ASTRA LAEKEMEDEL AKTIEBOLAG 发明人 JOHANSSON, KARL N.;LINDBORG, BJOERN G.;NOREN, JAN-OLOF
分类号 C07D473/00;A61K31/52;A61K31/522;A61P31/12;A61P31/22;A61P35/00;A61P35/02;C07C43/174;C07C43/178;C07C43/315;C07D;C07D473/18 主分类号 C07D473/00
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