| 摘要 |
of the disclosure: The invention relates to a process for the preparation of compounds containing carboxamide groups, in particular peptides, by reaction of compounds which contain a carboxyl group, in the presence of dialkylphosphinic anhydrides, with compounds which contain a free amino group, which comprises maintaining the hydrogen ion concentration of the reaction mixture within a defined range during the reaction by metering in a base and, after the reaction is complete, eliminating, where appropriate, radicals introduced to protect other functional groups. |
