发明名称 |
Polyamide resin and method for preparation of reagents for immunodiagnostic use |
摘要 |
A polyamide resin for use in peptide and protein synthesis, and a method of preparing and using same. The polyamide resin is prepared by cross-linking a dimethylacrylamide monomer by co-polymerization with a functional monomer in an aqueous solution, emulsifying the aqueous solution in an organic solvent and isolating the polyamide resin beads formed by adding an initiator and a promoter. The beads are used as a solid phase for peptide and protein synthesis according to methods known in the art. The conjugate of the polyamide resin and the synthesized peptide or protein is used directly for immunoassays or immunization without the need for separation of the peptide or protein from the resin and subsequent purification.
|
申请公布号 |
US5028675(A) |
申请公布日期 |
1991.07.02 |
申请号 |
US19890309914 |
申请日期 |
1989.02.10 |
申请人 |
SOUTHWEST FOUNDATION FOR BIOMEDICAL RESEARCH;BAYLOR COLLEGE OF MEDICINE |
发明人 |
KANDA, PATRICK;KENNEDY, RONALD C.;SPARROW, JAMES T. |
分类号 |
A61K47/48;C08F220/56;G01N33/543 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|