PROCESS FOR THE PRODUCTION OF N-(PYRROLO/2,3-D/PYRIMIDINE-3-YL-ACYL)-GLUTAMINE-ACID DERIVATIVES
摘要
<p>N-(Acyl)glutamic acid derivatives in which the acyl group is substituted with 4-hydroxypyrrolo[2,3-d]pyrimidin-3-yl group are antineoplastic agents. A typical embodiment is N-[4-(2-{4-hydroxy-6-aminopyrrolo[2,3-d]pyrimidin-3-yl}-ethyl)benzoyl] -L-glutamic acid.</p>