发明名称 MEDICAL PREPARATION
摘要 <p>Pharmaceutical preparation consisting of one or more active ingredients and an excipient which solidifies at temperatures between 20 and 80 DEG C and is water soluble, characterized in that it is an isotropic solution in which a) the active ingredient is dissolved in monomolecular or ionic form in the excipient, b) the active ingredient is present in its native conformation and/or its biologically active chiral (enantiomeric) conformation, c) the active ingredient has a mol fraction of 0.001 to 0.67 at 37 DEG C, d) at body temperature, the excipient is molten, single-phase and isotropic, e) the isotropic solution, consisting of excipient and active ingredient, solidifies at ambient temperature, f) the solidified solution is crystalline or non-crystalline or it contains the active ingredient in crystalline form or the latter can crystallize out of the solidified solution, g) the monomolecular or ionic solution has an osmotic pressure and depresses the molar freezing point, h) the dissolved active ingredient present in the polymer electrolyte has a temperature-dependent specific conductivity. A process for obtaining this pharmaceutical preparation is also described.</p>
申请公布号 HU904479(D0) 申请公布日期 1991.06.28
申请号 HU19900004479 申请日期 1990.05.16
申请人 MEDICE CHEM.-PHARM. FABRIK PUETTER GMBH. UND CO. KG,DE 发明人 PARADIES,HENRICH H.,DE;SCHNEIDER,BERND,DE;HANNA,SAMIR B.,US
分类号 A61K31/19;A61K9/08;A61K9/14;A61K9/48;A61K31/40;A61K31/55;A61K31/557;A61K31/704;A61K38/00;A61K39/00;A61K39/395;A61K47/10;A61K47/14;A61K47/34;B01J29/70;C07B41/08;C07B53/00;C07B61/00;C07C51/15;C07C51/16;C07C53/132;C07C53/23;C07C57/30;C07C57/58;C07C59/13;C07C59/135;C07C59/52;C07C59/56;C07C59/64;C07C59/68;C07C69/612;C07C69/732;C07C69/734;C07C69/736 主分类号 A61K31/19
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