| 摘要 |
<p>A method for inhibiting growth of Pneumocystis carinii in a mammalian host, which comprises administering to the host an amount of a 1-phenyl-s-triazine effective to inhibit growth of P. carinii. Preferred compounds have formula (I), wherein X, Y, and Z are independently selected from the group consisting of hydrogen, hydroxy, halogen, lower alkyl, aryl lower alkyl, lower alkylthio, lower alkyloxy, and trifluoromethyl; R1 is lower alkyl; and R2 is hydrogen or methyl; as well as compounds formed by reaction of an organic or inorganic acid with a triazine of this formula to form an amide or acid addition salt. Administration of precursors which form the triazine in vivo is also within the scope of the invention.</p> |
