| 发明名称 |
COMPOUNDS FOR THE REVERSAL OF MULTIDRUG RESISTANCE OF CANCER CELLS AGAINST CYTOTOXIC DRUGS |
| 摘要 |
A compound comprising toremifene or its metabolite N-demethyltoremifene or 4-hydroxytoremifene, or a non-toxic pharmaceutically acceptable salt thereof may be used for the reversal of multidrug resistance of cancer cells to cytotoxic drugs in the treatment of cancer with at least one cytotoxic drug. |
| 申请公布号 |
ZA9006670(B) |
申请公布日期 |
1991.06.26 |
| 申请号 |
ZA19900006670 |
申请日期 |
1990.08.22 |
| 申请人 |
ADRIAN LLEWELLYN HARRIS;LAURI VEIKKO MATTI KANGAS;MICHAEL WILLIAM DEGREGORIO |
发明人 |
ADRIAN LLEWELLYN HARRIS;LAURI VEIKKO MATTI KANGAS;MICHAEL WILLIAM DEGREGORIO |
| 分类号 |
A61K31/13;A61K31/135;A61K31/70;A61K31/7028;A61K31/7034;A61K31/704;A61K45/00;A61P35/00;A61P43/00;C07H15/244 |
主分类号 |
A61K31/13 |
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