发明名称 |
ANALOGIFREMGANGSMAADE TIL FREMSTILLING AF SPERGUALINBESLAEGTEDE FORBINDELSER |
摘要 |
<p>This invention relates to a novel spergualin-related compound and a process for the production thereof. The novel compound, which has a high antitumor activity, is represented by the general formula <IMAGE> (I) wherein R1 represents a hydrogen atom, hydroxyl group, or an aliphatic acyloxy group having 1 to 10 carbon atoms, R2 represents an amino acid residue (except for the residue of alpha -hydroxyglycine) formed by removing one hydrogen atom and hydroxyl group from respectively the alpha - or omega -amino group and the alpha -carboxyl group of an alpha - or omega -amino acid, said amino acid residue forming acid amide linkages with the adjacent carbonyl group and amino group, and m is an integer of 4 to 6.</p> |
申请公布号 |
DK160089(C) |
申请公布日期 |
1991.06.24 |
申请号 |
DK19830003985 |
申请日期 |
1983.09.01 |
申请人 |
MICROBIAL CHEMISTRY RESEARCH FOUNDATION |
发明人 |
UMEZAWA, HAMAO;TAKEUCHI, TOMIO;NISHIZAWA, RINZO;TAKAHASHI, KATSUTOSHI;NAKAMURA, TERUYA;UMEDA, YOSHIHISA |
分类号 |
A61K31/155;A61K31/16;A61K31/165;A61K31/195;A61K31/40;A61K31/415;A61P35/00;A61P35/02;C07C67/00;C07C239/00;C07C279/04;C07C279/14;C07D207/16;C07D209/48;C07D233/54;C07D233/64;(IPC1-7):C07C279/12 |
主分类号 |
A61K31/155 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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