| 摘要 |
A method and apparatus are disclosed for transdermal inotophoretic delivery of ionic species, such as a drug in ionic form, in which electrical pulses having controlled, distinctive, dual-segment waveform characteristics are applied. The therapeutic pulses are generated at a predetermined frequency and have a predetermined pulse width. First (20) and second (22) pulse segment generator means generate pulse segments which are applied to the patient skin through active (16) and indifferent (18) electrodes. The electrical attributes of each pulse segment, including amplitude and duration, are controlled to produce the desired, pulsed output waveform.
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