发明名称 LTB4 SYNTHESIS INHIBITORS
摘要 ?7N This invention relates to a compound of the formula: or a pharmaceutically acceptable salt thereof wherein X is oxygen, sulfur, -CH=CH-or -CH=N-; wherein R1 is alkyl, alkenyl or alkynyl of about 1 to 20 carbon atoms; wherein R is -CO2R2, tetrazole, methylsulfonamide or benzenesulfonamide, wherein R2 is hydrogen, alkyl of 1 to 6 carbon atoms or a pharmaceutically acceptable cation and R3 is hydroxyl or halogen, having utility as LTB4 synthesis inhibitors.
申请公布号 CA2032393(A1) 申请公布日期 1991.06.19
申请号 CA19902032393 申请日期 1990.12.17
申请人 SEARLE (G.D.) & CO. 发明人 DJURIC, STEVAN W.;HAACK, RICHARD A.;MIYASHIRO, JULIE M.
分类号 A61K31/18;A61K31/19;A61K31/235;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/44;A61K31/4402;A61K31/4427;A61K31/443;A61K31/4433;A61P1/04;A61P29/00;A61P43/00;C07C59/70;C07C59/74;C07C65/19;C07C65/30;C07C65/32;C07C65/38;C07C69/712;C07C69/76;C07C311/51;C07D213/76;C07D213/79;C07D257/04;C07D307/66;C07D307/68;C07D333/34;C07D333/38;C07D401/04;C07D405/04;C07D409/04;(IPC1-7):C07C65/38;A61K31/33 主分类号 A61K31/18
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