发明名称 |
Stabilization and maintenance of the nerve growth factor biological activity by use of natural gangliosides or derivatives thereof. |
摘要 |
<p>The present invention concerns new, stable and biologically active complex compounds between the proteins and gangliosides, namely, stable and biologically active complexes between the beta subunit of Nerve Growth Factor ( beta NGF) and natural gangliosides or their semisynthetic analogues such as carboxy esters and amides; as well as pharmaceutical compositions containing such complexes, their therapeutic uses and a process for their manufacture.</p> |
申请公布号 |
EP0433113(A1) |
申请公布日期 |
1991.06.19 |
申请号 |
EP19900403221 |
申请日期 |
1990.11.14 |
申请人 |
FIDIA S.P.A. |
发明人 |
DELLA VALLE, FRANCESCO;ROMEO, AURELIO;CALLEGARO, LANFRANCO;LEON, ALBERTA |
分类号 |
A61K38/00;A61P25/00;A61P25/28;A61P37/00;C07H15/10;C07K14/00;C07K14/48;C07K14/52 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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