发明名称 Serotonin antagonists, their preparation and the medicaments containing them
摘要 Compounds of formula <IMAGE> in which - R1 represents . a 1,2,3,6-tetrahydro-1-pyridyl radical substituted in the 4-position by an optionally substituted phenyl, optionally substituted 3-indolyl or 5-hydroxy-3-indolyl radical, . a 1-piperazinyl radical substituted in the 4-position by a 2-pyridyl, 1,2-benzisoxazol-3-yl, 1,2-benzisothiazol-3-yl or optionally substituted phenyl radical, . a piperidino radical substituted in the 4-position by an optionally substituted phenyl, bis(4-fluorophenyl)methylene, 4-fluorobenzoyl, optionally substituted 2-oxo-1-benzimidazolinyl, optionally substituted 3-indolyl or 5-hydroxy-3-indolyl radical or by two phenyl radicals or a hydroxy radical and an optionally substituted phenyl radical - R2 represents an SO2R4 radical in which R4 represents an alkyl or phenyl radical, - R3 represents a phenyl or naphthyl radical, - or else R2 and R3 form, together with the nitrogen atom to which they are attached, a ring, - n is equal to 2, 3 or 4, processes for their preparation and the medicaments containing them.
申请公布号 FR2655652(A1) 申请公布日期 1991.06.14
申请号 FR19890016459 申请日期 1989.12.13
申请人 RHONE POULENC SANTE 发明人 MALLERON JEAN-LUC;PEYRONEL JEAN-FRANCOIS;TRUCHON ALAIN
分类号 C07D227/087;C07D275/06;C07D279/02;C07D285/16;C07D295/13;C07D401/06;C07D401/12;C07D401/14;C07D413/12;C07D417/06;C07D417/12;C07D417/14;C07D471/06;C07D513/06 主分类号 C07D227/087
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