| 发明名称 |
NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS |
| 摘要 |
Triiodinated isophthalamide derivatives, useful as X-ray contrast agents, having at least one amide group derived from the amino-alcohol, 3-(N-2-hydroxyethyl)amino-1,2-propanediol, which provides high water solubility and low mammalian toxicity, and methods of preparing them. Methods of preparing 3-(N-2-hydroxyethyl)amino-1,2-propanediol are provided.
|
| 申请公布号 |
CA2071505(A1) |
申请公布日期 |
1991.06.14 |
| 申请号 |
CA19902071505 |
申请日期 |
1990.12.11 |
| 申请人 |
MALLINCKRODT, INC. |
发明人 |
KNELLER, MILLS;LIN, YOULIN;WHEATLEY, JAMES |
| 分类号 |
A61K49/04;C07C237/42;C07C237/46;C07D207/26;C07D207/27;C07D207/273;(IPC1-7):C07C237/46;C07C213/08;C07C215/12 |
主分类号 |
A61K49/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
