METHOD OF PRODUCING COMPACTED DISPERSABLE SYSTEMS

摘要

Floss spun from a mixture of a saccharide and an oleaginous substance which includes a medicament distributed on or through the fibers is compacted and chopped by passing through a conventional ''food grinder'' or equivalent having an auger feed to a cutter and orifice plate outlet. The enclosed volume of the end product is less than 30 % and preferably less than 15 % of the as-spun volume of the floss. This volume reduction is accomplished without destroying the colloidal-like behavior of the product. The compressed particles are readily metered for producing dosage units within required tolerances.