发明名称 2-SUBSTITUTED 4,5-DIPHENYL-IMIDAZOLES
摘要 2071497 9109030 PCTABS00005 Imidazole derivatives of the formula (I): ¢DPIM!-S-W-Y, wherein ¢DPIM! represents a group of formula (DPIM), wherein R and R1 represent hydrogen, halogen or alkyl, W represents straight chain alkylene of 1 to 6 carbon atoms optionally substituted by alkyl, Y represents a group of formulas (II), (III), (IV), (V), (VI) and salts thereof, are inhibitors of acyl coenzyme-A:cholesterol-O-acyl transferase useful for the conditions such as atherosclerosis, hyperlipidaemia, cholesterol or ester storage disease and atheroma in vein grafts.
申请公布号 CA2071497(A1) 申请公布日期 1991.06.13
申请号 CA19902071497 申请日期 1990.12.11
申请人 RHONE-POULENC SANTE;RHONE POULENC RORER SA 发明人 BRIDGE, ANDREW W.;HARRIS, NEIL V.;LYTHGOE, DAVID J.;SMITH, CHRISTOPHER
分类号 A61K31/415;A61K31/435;A61K31/535;A61K31/54;A61P3/08;A61P43/00;C07D233/84;C07D401/12;C07D403/12;C07D413/12;C07D417/12;(IPC1-7):C07D403/12;A61K31/395 主分类号 A61K31/415
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