SUBSTITUTED AMINE DERIVATIVES, THEIR PRODUCTION AND USE

摘要

Substituted amino derivatives represented by the formula: wherein R<1> and R<2> each stand for an acyclic hydrocarbon residue or an alicyclic hydrocarbon residue; R<3> and R<4> each stand for hydrogen or a hydrocarbon residue optionally containing hetero-atom(s); A stands for a carbon chain having two or more carbon atoms optionally containing ether linkage or sulfide linkage, which may be substituted and which may per se form a ring; X<1> and X<2> each stand for oxygen atom or sulfur atom; and Y stands for amino group or an organic residue bonded through nitrogen atom, which may form a ring by combining with a carbon atom constituting A; and their salts have anti-arrhythmic activity and are useful for prevention and treatment of a variety of arrhythmias.