发明名称 NOVEL PYRIDONE DERIVATIVE, ITS PREPARATION METHOD AND INTERMEDIATE, THEIR USE AS PHARMACEUTICAL AGENT AND COMPOSITION CONTAINING SAME
摘要 Compounds of the formula (I): <IMAGE> in which: - either E and G form <IMAGE> which represents: <IMAGE> in which R represents hydrogen, alkyl, alkenyl or alkynyl, which is optionally substituted, free carboxyl, esterified carboxyl or carboxylic salt, acyl, alkoxy, hydroxy, amino, alkylamino, dialkylamino, acyloxy, cyano, carbamoyl or halogen -- Y represents carbocyclic aryls, heteromonocyclic aryls or condensed heterocyclic aryls which are optionally substituted, <IMAGE> - or E represents -CO2R3, in which R3 represents hydrogen or alkyl and G represents <IMAGE> -- A represents: - either a carbocyclic radical which is optionally substituted, - or <IMAGE> where B represents: - hydrogen, - aryl or arylalkyl, or - cycloalkyl, which are optionally substituted, - alkyl, alkenyl, alkynyl or alkyloxy which are optionally substituted, -- R1 and R2 represent hydrogen, alkyl, alkenyl or alkynyl which are optionally substituted, or R1 and R2 form with the nitrogen atom a 5-, 6- or 7-membered heterocycle optionally containing another heteroatom and optionally substituted, their preparation and their use as medicines.
申请公布号 JPH03133957(A) 申请公布日期 1991.06.07
申请号 JP19900275504 申请日期 1990.10.16
申请人 ROUSSEL UCLAF 发明人 FURANSOWA KUREMANSU;MISHIERU FUORUTAN;ODEIRU RU MARUTORE
分类号 C07D295/12;A61K31/44;A61K31/4412;A61K31/4427;A61K31/445;A61K31/451;A61P9/06;A61P9/12;A61P25/02;A61P25/04;A61P29/00;C07D211/40;C07D211/76;C07D211/86;C07D295/125;C07D295/13;C07D295/135;C07D401/06;C07D401/08;C07D401/10 主分类号 C07D295/12
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