Xanthine compound, method for preparing thereof, and a pharmaceutical composition comprising the same.

摘要

A novel xanthine compound having bronchodilating and brain function improving activity represented by the following formula (I) and (II): <CHEM> wherein R<1> represents a hydrogen atom, 4-methoxybenzyl group, a straight- or branched-chain alkyl group having 1 to 6 carbon atoms, or a cycloalkyl group having 3 to 6 carbon atoms; R<2> represents a hydrogen atom, a straight- or branched-chain alkyl group having 1 to 6 carbon atoms, or a cycloalkyl group having 3 to 6 carbon atoms; n represents an integer of from 1 to 4; and A represents -COCH3 or - C(OR<3>)(OR<4>)CH3 in which R<3> and R<4> independently represents an alkyl group having 1 to 3 carbon atoms or R<3> together with R<4> represents a polymethylene group having 2 to 4 carbon atoms is disclosed. Also disclosed are a pharmacologically acceptable salt of the same, method for preparing the same, and a pharmaceutical composition for the treatment of respiratory tract disease or brain disfunction comprising the effective amount of same.