| 摘要 |
A method of treating hyperproliferative skin diseases, such as psoriasis, using a compound of formula <IMAGE> I wherein R1 is hydrogen when R2 is hydroxy, and R1 is methyl when R2 is hydrogen; and A is alkyl; cycloalkyl; alkenyl; alkyl substituted with trifluoromethyl; phenyl; halophenyl; phenyl-C1-3 alkyl; phenyl-C1-3 alkyl substituted on the phenyl with 1 to 3 substituents selected from the group consisting of halo, C1-3 alkyl, and C1-3 alkoxy; or A is <IMAGE> wherein R3 is hydrogen or <IMAGE> R4 is hydrogen or methyl, and n is 1 to 5, or the corresponding hydroxy acid of formula <IMAGE> II or a pharmaceutically acceptable salt of said acid, an alkyl ester of said acid, an acetylamino-substituted-C1-4 alkyl ester of said acid, a phenyl-dimethylamino ester of said acid or a alpha -monoglyceride of said acid.
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