发明名称 Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol
摘要 An antibiotic agent produced by the cultivation of Zalerion arboricola which is a cyclic lipopeptide with very high activity against human pathogens and of very low mammalian toxicity and its production and isolation are described.
申请公布号 US5021341(A) 申请公布日期 1991.06.04
申请号 US19900492026 申请日期 1990.03.12
申请人 MERCK & CO., INC. 发明人 GIACOBBE, ROBERT A.;TKACZ, JAN S.;MASUREKAR, PRAKASH S.;KAPLAN, LOUIS;SOSA, MARGARET S.
分类号 A61K38/00;C07K7/56;C12P21/04 主分类号 A61K38/00
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