发明名称 |
AMINOCARBONYLCARBAMATES RELATED TO PHYSOSTIGMINE, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS |
摘要 |
Aminocarbonylcarbamates related to physostigmine, a process for their preparation and their use as medicaments The present invention relates to various derivatives related to physostigmine of the formula I (see formula I) where Z is hydrogen, halogen or loweralkyl; R1 is loweralkyl, cycloalkyl or aryl; and R2 is loweralkyl or cycloalkyl; the 3aS-cis isomer or the 3aR-isomer thereof or a mixture of the two isomers including the racemic mixture, or a pharmaceutically acceptable acid addition salt thereof, and a process for their preparation. The compounds according to the invention are useful for enhancing cholinergic function, and as analgesic agents.
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申请公布号 |
CA2031079(A1) |
申请公布日期 |
1991.05.31 |
申请号 |
CA19902031079 |
申请日期 |
1990.11.29 |
申请人 |
HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED;HOECHST MARION ROUSSEL INC |
发明人 |
GLAMKOWSKI, EDWARD J.;CHIANG, YULIN;HAMER, RUSSELL R. L. |
分类号 |
A61K31/40;A61P25/04;A61P25/28;C07D487/04;(IPC1-7):A61K31/40 |
主分类号 |
A61K31/40 |
代理机构 |
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主权项 |
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地址 |
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