PREPARATION METHOD FOR alpha , beta -UNSATURATED KETONES

摘要

The present invention relates to a method for the preparation of alpha , beta -unsaturated ketones represented by general formula (II) (where R is as defined above) which comprises that aldehydes represented by general formula (III): RCHO (where R is as defined above) and acetone are reacted in the presence of one or two or more compounds selected from the group consisting of perhydroisoindole and pyrrolidine which may have substituents as catalysts, in a water solvent, at -40 DEG C to 60 DEG C, then acetone is distilled to remove, and a water-insoluble organic solvent is added to the remaining reaction solution to react in the presence of acid catalyst. Compound (II) is extremely important as intermediates for pharmaceuticals and agricultural chemicals.