发明名称 NUCLEINSYREPROBER INDEHOLDENDE EN FORBEDRET MOLEKYLAER OMSKIFTER SAMT ANALYSER OG KITS, HVORI DISSE INDGAAR
摘要 A probe for the detection of a nucleic acid target sequence containing a molecular switch comprising three essential elements: a probe sequence of 20-60 nucleotides surrounded by switch sequences of 10-40 nucleotides which are complementary to each other, wherein the state of the switch is useful for selectively generating a detectable signal if the probe is hybridized to a target; also, assays and kits utilizing such probes.
申请公布号 DK56091(A) 申请公布日期 1991.05.30
申请号 DK19910000560 申请日期 1991.03.27
申请人 PUBLIC HEALTH RESEARCH INSTITUTE OF THE CITY OF NEW YORK, I;SALK INSTITUTE FOR BIOLOGICAL STUDIES, THE 发明人 LIZARDI, PAUL M.;KRAMER, FRED RUSSELL;TYAGI, SANJAY;GUERRA, CESAR EDUARDO;BUYOLI, HILDA M. LOMELI;CHU, BARBARA C.;JOYCE, GERALD F.;ORGEL, LESLIE E.
分类号 C12N15/09;C12Q1/68;(IPC1-7):C12Q1/68 主分类号 C12N15/09
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