| 摘要 |
Acyclic terpene compounds useful as intermediates for producing sarcophytol A which have an anti-carcinogenic promotor activity and anti-tumor activity, which compounds are shown by the general formula (I): (I) ¢wherein R is a group of formula: , or (wherein R1 is cyano group or formyl group; R2 is a hydrogen atom or -CO2R3; R3 is C1 - C4 alkyl group; R4 is -C?CH or -CH=CH2 ); X is a hydrogen atom, hydroxyl group, a halogen atom, or a group of formula: -OR5 or -OSO2R6 (wherein R5 is a hydrogen atom, 1-alkoxyalkyl group, tetrahydrofuryl group, tetrahydropyranyl group or acyl group, silyl group substituted with C1 - C5 alkyl group or phenyl group; R6 is C1 - C4 alkyl group optionally substituted with halogen atom, or phenyl group optionally substituted with C1 - C4 alkyl group); and n is an integer of 0 to 2 with the proviso that when R is a group of formula: or X must be -OR5 and n must be 0; when R1 is formyl group, X is not a halogen atom or -OS02R6; when R5 is a hydrogen atom, R6 is not a hydrogen atom; and when R5 is 1-ethoxyethyl group, R3 is not a methyl group!.
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