Implant material composition, preparation thereof as well as uses thereof and implant product obtainable therefrom.

摘要

The invention relates to an implant material composition for restoring bone tissue in a human or animal body. Said composition comprises a particulate biocompatible bone tissue substitute material distributed in a bioacceptable mixture of a) a water-based liquid and b) a monoglyceride and optionally c) a triglyceride, said ingredients a), b) and c) forming an L2-phase or a lamellary liquid crystalline phase and being present in such proportions within said phases that they are capable of being transformed into a cubic liquid crystalline phase or a reversed hexagonal liquid crystalline phase when contacted with an aqueous liquid. Thus, the phase conversion referred to imparts to the composition such a high viscosity that is works as an implant material as defined. There is also provided a method of preparing said composition comprising forming the L2 or lamellary phase and distributing the bone tissue substitute material therein. Moreover, there is provided a method of restoring lost bone tissue comprising applying the composition to a bone cavity and converting the same by contact with an aqueous liquid. The composition for use as an implant material composition as well as the use thereof for the manufacture of an implant product are also provided. Finally the invention relates to the restored implant bone tissue product obtainable from said composition by contact with said aqueous liquid.