PROCESS FOR MAKING COLLAGEN MEMBRANES FOR MEDICAL USE

摘要

Collagen membranes with desired properties are prepared by using a variety of gel-forming techniques in combination with methods for converting the gels to solid forms. One technique involves compressing a gel matrix under constant pressure to form a fibre network which is dried; another involves disrupting and centrifuging a matrix, harmonizing the precipitate auto or paste and casting and drying the paste. The properties of these membranes or other solid forms may be further altered by cross-linking the collagen preparation either after formation of the membrane or gel, or most preferably by mixing cross-linked collagen with solubilized collagen in the original mixture used to create the gel.