摘要 |
<p>A hair growth stimulant compsn. contains (a) an amine oxide; (b) a calmodulin inhibitor and/or a calcium antagonist. Pref. the amount of each component is (a) 0.0001-20% (wt.); (b) 0.00001-10% (wt.); and the ratio of (a)/(b) is 10,000/1 to 1/10,000 (wt.). P'ref. the amine oxide is a cpd. of formula (I) - (V): where R1 is 8-24C straight or branched alkyl or alkenyl; R2 and R3 are 6-18C straight or branched alkyl or alkenyl; n is 1-5. The calmodulin inhibitor is phenothiazine, butyrophenone, diphenylbutylamine, benzodiazepine, naphthalenesulphonamide, trifluperazine, chlorpromazine, amitriptyline, fluphenazine, pimozide, medazepam, protriptyline, chloride, chlordiazepoxide, tetracaine, promethazine, or benperidol etc.. The calcium antagonist is a 1,40dihydropyridine, benzothiazopine, piperazine, benzothiazole, bepridine or perhexiline deriv. etc.</p> |