| 发明名称 |
Specific binding agents. |
| 摘要 |
<p>A reshaped human antibody or reshaped human antibody fragment having specificity for human placental alkaline phosphatase (PLAP) is produced by transferring the complementarity determining regions (CDRs) from a murine anti-PLAP hybridoma cell line H17E2 into a human antibody variable region framework. The reshaped molecule can be used in the treatment or diagnosis of cancer</p> |
| 申请公布号 |
EP0429242(A2) |
申请公布日期 |
1991.05.29 |
| 申请号 |
EP19900312407 |
申请日期 |
1990.11.14 |
| 申请人 |
UNILEVER PLC;UNILEVER N.V. |
发明人 |
VERHOEYEN, MARTINE ELISA |
| 分类号 |
A61K38/00;A61K39/395;C07K7/06;C07K7/08;C07K16/00;C12N1/21;C12N5/10;C12N15/09;C12N15/13;C12P21/08;C12R1/19;C12R1/91;G01N33/53;G01N33/563;G01N33/573;G01N33/574 |
主分类号 |
A61K38/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
