| 发明名称 |
Benzoyl peroxide-quaternary ammonium lipophilic salicylate based pharmaceutical and cosmetic compositions and their use especially in treatment of acne |
| 摘要 |
A pharmaceutical or cosmetic composition for topical application comprises, in a physiologically acceptable support, the combination of benzoyl peroxide and at least one quaternary ammonium lipophilic salicylate having general formula (I): <IMAGE> (I) where: (i) R1, R2, R3 and R4 may be identical or different, representing a substituted or interrupted alkyl or cycloalkyl radical; (ii) R3 and/or R4 represent(s) the group: R8-OC2H3R7]n[OCH2CHOH-CH2]p where O</=n</=4 and p is 0 or 1; R8 represents H or an alkyl, alkenyl, alkylcycloalkyl or alkylanyl radical; (iii) R4 represents an alkylenephenyl radical; (iv), (v): R1 and R2 may form an aromatic or nonaromatic saturated or unsaturated heterocycle; (vi) R1, R2 and R3 together with nitrogen, may form polycyclic derivatives; and R5 represents a group having the formula: <IMAGE> where n may vary from 0 to 10.
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| 申请公布号 |
US5019567(A) |
申请公布日期 |
1991.05.28 |
| 申请号 |
US19880276155 |
申请日期 |
1988.11.23 |
| 申请人 |
L'OREAL |
发明人 |
PHILIPPE, MICHEL;HOCQUAUX, MICHEL;SEBAG, HENRI;BECK, IRINA;LAUGIER, JEAN P. |
| 分类号 |
A61K8/30;A61K8/00;A61K8/04;A61K8/33;A61K8/365;A61K8/38;A61K8/40;A61K8/41;A61K8/49;A61K31/00;A61K31/075;A61K31/09;A61K31/14;A61K31/19;A61K31/205;A61K31/435;A61K31/60;A61K33/40;A61P17/00;A61Q19/00;C07C63/06;C07D213/02 |
主分类号 |
A61K8/30 |
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